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Educational requirements: Master's degree or above, with a major background in chemistry, pharmacy, analytical chemistry, bioengineering, biotechnology or related fields.
Work experience:
1. At least 1-3 years of relevant work experience, with preference given to those with experience in drug development, bioanalysis or mass spectrometry.
2. Recent graduates who have published their research findings in international academic journals in the field of mass spectrometry analysis may also be considered.
Professional skills:
1. Proficient in mass spectrometry analysis techniques, capable of skillfully operating and maintaining equipment such as liquid chromatography-mass spectrometry (LC-MS/MS), and independently completing experimental procedures including sample pretreatment, instrument parameter optimization, data acquisition, and analysis. Possesses extensive experience in quantitative and qualitative mass spectrometry analysis. 2. Proficient in chromatographic techniques, such as high-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UPLC), and capable of selecting, maintaining, and optimizing chromatographic columns to achieve effective separation and detection of target compounds in complex samples.
4. Be familiar with the processing and preparation methods of biological samples (such as blood, urine, tissue, etc.) to ensure the quality and stability of samples and provide a reliable basis for mass spectrometry analysis.
5. Understand the knowledge and techniques related to drug metabolism, pharmacokinetics (PK), and bioanalysis, and be able to participate in PK studies in drug development projects, assisting in experimental design and data analysis.
Other requirements:
1. Possess independent analytical and experimental design capabilities, and be able to design scientific and reasonable experimental schemes according to project requirements.
2. Independently solve problems encountered during experiments, possess strong problem-solving and experimental summarization abilities, be able to conduct in-depth analysis of experimental results, summarize lessons learned, and propose improvement measures.
3. Possess strong English reading, communication, and writing skills; be able to fluently read and understand professional English literature; and keep abreast of the latest mass spectrometry analysis technologies and development trends both domestically and internationally.
4. Possesses strong teamwork and communication skills, able to collaborate closely with team members, share experience and knowledge, and jointly advance project progress; possesses excellent time management skills, able to reasonably arrange work tasks and ensure timely project completion.
6. Possess laboratory safety and environmental awareness, strictly abide by laboratory safety operating procedures, properly dispose of experimental waste, and ensure a safe and clean laboratory working environment.
[Note] Personnel who can accept conducting experiments in external laboratories will be given priority consideration.
(Location: Jiaotong University Laboratory, Minhang District; working days at external laboratories will be arranged according to actual work requirements.)
Salary range: 10-20k
(Please indicate the job title when submitting your resume)
Job Responsibilities:
1. Conduct research on current market drugs to select potential drug targets for design;
2. Use AI algorithms for protein design and structure prediction methods for forecasting;
3. Utilize conventional molecular simulation tools and independently developed computational chemistry and artificial intelligence methods to conduct virtual screening, design, and optimization of protein drugs;
4. Analyze and interpret large-scale bioinformatics data to identify new therapeutic targets;
5. Collaborate closely with team members, iterate using experimental data, and advance the project.
6. Complete other tasks assigned by the supervisor.
Job requirements:
1. Preference will be given to candidates with experience in computer-aided drug design, computational chemistry/pharmacy, computational biology, or related fields.
2. Familiar with drug screening processes and methods;
3. Preference will be given to candidates with knowledge of AI-based protein drug design algorithms;
4. Proficient in structure- or ligand-based drug design software, such as Autodock, Amber, and other molecular dynamics simulation software;
5. Possesses excellent teamwork spirit;
6. Two days of in-person internship per week are possible.
(Please indicate the job title when submitting your resume)
Job Responsibilities:
1. Utilize conventional molecular simulation tools and independently developed computational chemistry and artificial intelligence methods to conduct virtual screening, design, and optimization of protein drugs;
2. Analyze and interpret large-scale bioinformatics data to identify new therapeutic targets;
3. Collaborate closely with team members, iterate using experimental data, and advance the project.
4. Complete other tasks assigned by the supervisor.
Job requirements:
1. Master's degree in computer-aided drug design, computational chemistry/pharmacy, computational biology, or a related field;
2. Familiar with drug screening and drug design methods and processes;
3. Proficient in structure- or ligand-based drug design software, such as Discovery Studio, Autodock, Amber, and other molecular dynamics simulation software;
4. Possesses excellent teamwork spirit.
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